Experience

Oct 2024 - present
Arm Ltd
Software Developer
Developer Ecosystems.
Feb 2022 - Oct 2024
Cambridge Intelligence
Software Developer
Graph visualisation SDK developer.
Jun 2021 - Feb 2022
Cambridge Intelligence
Graduate Software Developer
Graph visualisation SDK developer.
2019 - 2021
University College London (LMCB)
Post-doctoral Fellow
Laboratory of Prof. Jonathan Chubb.
2013 - 2014
The London Research Institute
Research assistant
Laboratory of Dr Nathan Goehring.

Education

2014 - 2018
The Francis Crick Institute
PhD candidate in quantitative cell biology
Laboratory of Dr Nathan Goehring.
2009 - 2012
University of Oxford
MBioChem
Undergraduate and Masters degree in Biochemisty (2:1).

Developer at Cambridge Intelligence

TypeScript/JavaScript developer working mainly on the company's graph visualisation software development kits, developing new features both for the SDKs, and their websites (using React, HTML, CSS). I have been lead developer on large projects, adding new features to the SDK, working on the technical implementation, project planning and management, coordinating team members, seeing projects through all the way from intial prototyping and feature design, to release.

I really enjoy working with different functions within the company, including product managers, platform engineers, QAs. I've also mentored several new starters to the company, and supported their onboarding.

Other duties include giving customer support, working with customer developers to help implement functionality, debug issues, etc.

Post-doctoral Fellow, Chubb lab

I managed my own project aimed at understanding how cells make decisions, using the social amaeba Dictyostelium discoidium as a model. Typically this involved live imaging using fluorescence micropscopy, and automated image analysis using Python and ImageJ/Fiji, and statistical analysis with Python (Pandas), as well as standard lab and molecular biology techniques.

A significant part of my project was to build agent-based models of cellular behaviour (C++), and comparing these to the experimental system.

PhD student, Goehring lab

I sucessfully completed a very independent PhD under the guidance of Nate Goehring, studying the PAR polarity network in C. elegans. This included a lot of live imaging using fluorescence confocal and TIRF micropscopy, genetics (including CRISPR), and developing novel biological techniques for the use in C elegans.

Publications

Nichols, J. M., Antolovic, V., Reich, J. D., Brameyer, S., Paschke, P., Chubb, J. R. (2020). Cell and molecular transitions during efficient dedifferentiation. ELife, 9. https://doi.org/10.7554/eLife.55435

Reich, J. D., Hubatsch, L., Illukkumbura, R., Peglion, F., Bland, T., Hirani, N., Goehring, N. W. (2019). Regulated Activation of the PAR Polarity Network Ensures a Timely and Specific Response to Spatial Cues. Current Biology. https://doi.org/10.1016/J.CUB.2019.04.058

Reich, Jacob Dietrich; (2019) Activation of the PAR polarity system in the C. elegans embryo. Doctoral thesis (Ph.D), UCL (University College London) https://discovery.ucl.ac.uk/id/eprint/10072620/

Hubatsch, L., Peglion, F., Reich, J. D., Rodrigues, T. L., Hirani, N., Illukkumbura, R., Goehring, N. W. (Accepted, 2019). A cell size threshold limits cell polarity and asymmetric division potential. Nature Physics. https://www.nature.com/articles/s41567-019-0601-x

Rodriguez, J., Peglion, F., Martin, J., Hubatsch, L., Reich, J. D., Hirani, N., Goehring, N. W. (2017). aPKC Cycles between Functionally Distinct PAR Protein Assemblies to Drive Cell Polarity. Dev Cell, 42(4), 400415 e9. https://doi.org/10.1016/j.devcel.2017.07.007